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Fibroblast-Adipocyte Interaction by Mariam El-Hattab, Ms.
El-Hattab, Mariam
Graduate Student
Biomedical Engineering Center for Computer Aided Design
Cell and Tissue Engineering and Wound Healing
2018-08-08
2020 submissions
Seamans Center, Iowa City, IA
Fibroblasts are collagen producing cells involved in the wound healing process and respond to biochemical and mechanical cues that direct their activity during healing. Adipocytes are typically known to be stagnant and are involved in hormonal and thermo-regulatory mechanisms. Recently however, adipocytes have been shown to be influence fibroblast activity during wound healing and may themselves produce collagen. This image shows a fibroblast cell spheroid (left) interacting with an adipocyte cell spheroid (right). Cells are shown in red and their collagen production is shown in green. Fibroblasts and adipocytes in co-culture migrate preferentially towards one another and radially outwards as time progresses, with this image showing their interactions after 7 days in culture. Each spheroid produces collagen in a pattern that mimics the corresponding cell migration.
fibroblast adipocyte collagen
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University of Iowa. College of Engineering. NEXUS Program University of Iowa. Lichtenberger Engineering Library Virgil M. Hancher Auditorium
Attribution-NonCommercial 2.0 (CC BY-NC 2.0) https://creativecommons.org/licenses/by-nc/2.0/
Contact Kari Kozak in the Litchenberger Engineering Library at the University of Iowa: http://www.lib.uiowa.edu/eng/contact/
Fibroblast-Adipocyte Interaction (Horizontal).jpg
Still Image
scientific illustrations (images)
